Author

Joshua Vollrath

Goethe University FrankfurtORCID 0000-0002-6673-3050Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein sequence· 1

Frequent Co-Authors

Julian D. LangeriD· 2 shared Ansgar A. WegeneriD· 1 shared Christian RenziD· 1 shared Eva-Maria Leibrock· 1 shared F. J. SorrelliD· 1 shared H. J. BaileyiD· 1 shared Helle D. UlrichiD· 1 shared Ivan ĐikićiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Julian D. LangerORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 13, 2026

SUMO paralogues differentially affect phase separation and aggregation of intrinsically disordered proteins

Philipp Christian Schönberger, Supriyo Naskar, Oliver Ordowski…·Helle D. Ulrich

This study shows SUMO1 and SUMO2 differentially regulate TDP-43 phase separation and aggregation, with SUMO1 inhibiting and SUMO2 promoting liquid-like states that prevent aggregation.

1 citation

protein sequence

𝕏 PostBluesky

BiophysicsbioRxivPreprintJan 18, 2024

Engineering CRBN for rapid identification of next generation binders

H. J. Bailey, Jonathan Eisert, Joshua Vollrath…·Ivan Đikić

This paper introduces a new CRBN construct for efficient binder discovery, showing it outperforms existing constructs in binding and production, and applies it to identify potent CRBN binders from a large compound library.

3 citations

humanexperimental assay

𝕏 PostBluesky