Author

Till Baar

University of CologneORCID 0000-0002-6744-1463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Achim TreschiD· 2 shared Chrysa NikopoulouiD· 1 shared David KöhleriD· 1 shared Jason M. Müller· 1 shared Katharina MoosiD· 1 shared Kerstin C. Maier· 1 shared Kristina ŽumeriD· 1 shared Matthias C. SchmidiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Achim TreschORCID

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2 papers

Recent·Most cited

Systems BiologyPLoS Computational BiologyPeer-reviewedMay 16, 2024

Nuclear export is a limiting factor in eukaryotic mRNA metabolism

Jason M. Müller, Katharina Moos, Till Baar…·Achim Tresch

This study quantifies mRNA synthesis, nuclear export, and degradation rates genome-wide, finding nuclear export is slow and cytosolic degradation is fast, with some transcripts using alternative export pathways.

19 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintOct 12, 2023

Dimension Reduction by Spatial Components Analysis Improves Pattern Detection in Multivariate Spatial Data

Niklas Kleinenkuhnen, David Köhler, Till Baar…·Achim Tresch

The paper introduces SPACO, a method for dimension reduction in spatial transcriptomics data that improves pattern detection by maximizing Moran's I and outperforms PCA.

DOI 10.1101/2023.10.12.562016

spatial transcriptomicsstatistical model

𝕏 PostBluesky