Ke Du

This paper develops a low-input, ultrasensitive diagnostic platform for detecting Avocado Sunblotch Viroid using RPA-CRISPR and nanopore-array fluorescence readout, achieving a detection limit of 1.68 copies/L.

This paper develops a nano-sieve platform for on-chip Raman detection of nanocubes, achieving enhanced signal amplification and multiplexed sensing.

This study shows that gold nanoparticle shape affects toxicity in algae, with nanostars causing more severe cellular and molecular damage than nanospheres.

This paper develops a silicon micropillar-enhanced CRISPR biosensor for detecting drug-resistant bacteria, achieving high sensitivity and specificity for MRSA.

This paper introduces a CRISPR-on-beads assay for rapid, sensitive, and specific detection of MRSA bacterial DNA using isothermal amplification, CRISPR cleavage, and magnetic bead signal amplification.

This paper demonstrates a biosensing platform using a silicon nanopillar metasurface coupled with LSPR mediated by cephalexin antibiotics, achieving a 22 nm wavelength shift for sensitive detection.

The paper introduces MFAST, a diagnostic chip for rapid, sensitive, and specific detection of Leishmania species, enabling duplex detection and stable performance in low-resource settings.

This study develops a durable antimicrobial surface (DAMS) using 3D-printed microstructures and ZnO nanoflowers, showing over 90% bacterial reduction after 12 hours and effectiveness after abrasion.

This study develops a FRET-CRISPR biosensor with micropillars for HPV 16 DNA detection, showing improved sensitivity and addressing microfluidic bubble issues.

This paper introduces a nano-sieve device for MRSA purification and detection using CRISPR, achieving a 15x concentration factor and 100 CFU/mL LOD.