GeneticsbioRxivPreprint
Use of a novel knock-in allele of Pkd1 identifies nicotinamide nucleotide dehydrogenase as a mitochondrial binding partner of polycystin-1
Cheng-Chao Lin, Luís F. Menezes, Elisabeth Pearson…·Gregory George Germino
The paper generates a new mouse model to study Polycystin-1's mitochondrial localization and function, identifying Nnt as a binding partner and showing NAC treatment benefits in Nnt+/+ mice.
DOI 10.1101/2022.04.08.487705