Siddappa N. Byrareddy

The paper identifies IL-17A, STAT1, CEBPB, and cGAS-STING as key drivers of HIV-associated neuroinflammation using HIV-infected cerebral organoids and validates findings in a primate model.

The paper compares cytokine-chemokine profiles induced by neurovirulent and non-neurovirulent HIV-1 strains and their Tat proteins, showing differential inflammatory responses.

The paper investigates tissue-specific metabolic reprogramming and gut dysbiosis in hamsters infected with SARS-CoV-2 variants, revealing differences in viremia, metabolic responses, and microbiota composition between delta and omicron variants.

This study shows morphine suppresses immune responses and alters brain myeloid gene expression in SIV-infected macaques, promoting neuropathogenesis.

The paper identifies and evaluates two potent SARS-CoV-2 entry inhibitors through computational screening and in vitro testing, showing synergy with remdesivir.

The paper identifies factors contributing to the higher infectivity of SARS-CoV-2 variants using bioinformatics and structural analysis.

This study shows that chronic morphine administration reduces SIV reservoirs in peripheral blood and lymph nodes but increases them in CNS microglia/macrophages in SIV-infected rhesus macaques.

This study maps N-glycans on ZIKV E proteins and shows their role in viral entry via host lectins, highlighting their importance in pathogenesis.