Author

Matheus Vitor Ferreira Ferraz

Universidade Federal de PernambucoORCID 0000-0002-6958-3115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Rebecca C. WadeiD· 2 shared Adriele Jéssica do Carmo SantosiD· 1 shared Gabriel Luz WallauiD· 1 shared Giulia PaiardiiD· 1 shared Isabelle F. T. VianaiD· 1 shared Marco RusnatiiD· 1 shared Rafael DháliaiD· 1 shared Roberto Dias LinsiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Rebecca C. WadeORCID

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2 papers

Recent·Most cited

BiophysicsPLoS Computational BiologyPeer-reviewedApr 21, 2025

Design of nanobody targeting SARS-CoV-2 spike glycoprotein using CDR-grafting assisted by molecular simulation and machine learning

Matheus Vitor Ferreira Ferraz, Wenny Camilla dos Santos Adan, Tayná Evily de Lima…·Roberto Dias Lins

This paper designs a high-affinity nanobody against SARS-CoV-2 spike protein using CDR-grafting combined with molecular simulation and machine learning.

7 citations

virusprotein structure

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BiophysicsProceedings of the National Academy of SciencesPeer-reviewedOct 14, 2024

The accomplices: Heparan sulfates and N-glycans foster SARS-CoV-2 spike:ACE2 receptor binding and virus priming

Giulia Paiardi, Matheus Vitor Ferreira Ferraz, Marco Rusnati, Rebecca C. Wade

This paper uses molecular dynamics simulations to show that heparan sulfate and N-glycans stabilize the SARS-CoV-2 spike:ACE2 complex and promote viral entry by triggering structural changes.

15 citationstop 5%

humanstructural biology

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