Author
Yujie He
The University of Texas at AustinORCID 0000-0002-6984-3052Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2026-2026 · peak 5/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links5 papers
Recent·Most cited
- BioengineeringACS NanoPeer-reviewed
A High-Throughput Platform for Rapid Adaptation of DNA Aptamers to SARS-CoV-2 Evolution
Yujie He, Zhenglin Yang, Yu-An Kuo…·Hsin‐Chih Yeh
This paper develops a high-throughput platform to rapidly adapt DNA aptamers against evolving SARS-CoV-2 variants, identifying mutants with improved binding affinity and specificity.
DOI 10.1021/acsnano.6c08330 - BiophysicsACS SensorsPeer-reviewed
Fluorogenic Aptamer Optimizations on a Massively Parallel Sequencing Platform
Yu-An Kuo, Y.-I. Chen, Naseem Siraj…·Hsin‐Chih Yeh
This paper optimizes a DNA-based fluorogenic aptamer (D-FAP) using a screening-and-simulation pipeline on a repurposed sequencing platform, achieving improved fluorescence properties.
- BioengineeringbioRxivPreprint
Lifetime-based multiplexed detection of viral RNA using fluorogenic aptamers
Y R Chen, Yu-An Kuo, Yujie He…·Hsin‐Chih Yeh
This paper introduces a fluorescence-lifetime-based multiplexed detection strategy using fluorogenic aptamers to distinguish viral RNA targets with minimal cross-reactivity and spectral overlap.
2 citations - BioengineeringbioRxivPreprint
Mechanistic insights into the color transformation of a non-FRET substrate for RNase activity detection
Sohyun Kim, Soonwoo Hong, Jada N. Walker…·Hsin‐Chih Yeh
This paper identifies the mechanism of color change in DNA/AgNC substrates upon nucleolytic cleavage and demonstrates their application in sensitive virus detection.