Author

Deli Huang

Scripps Research InstituteORCID 0000-0002-6989-639XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Amanda Lee GaviniD· 1 shared Chunying CheniD· 1 shared David A. NemazeeiD· 1 shared Dongsheng LiuiD· 1 shared Fangkun Luan· 1 shared Fenglin GuoiD· 1 shared Guizhi Dong· 1 shared Hanjun ZhaoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Amanda Lee GavinORCID

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2 papers

Recent·Most cited

Cell BiologyAdvanced SciencePeer-reviewedDec 7, 2025

IgG-Bridging-Seeded Synergistic Aggregation of SARS-CoV-2 Spikes Underlies Potent Neutralization by A Low-Affinity Antibody

Niannian Lv, Peng Chen, Xiaobin Dai…·Yuhe Renee Yang

This paper identifies a low-affinity SARS-CoV-2 antibody, P5-1C8, that neutralizes Omicron JN.1 through IgG-mediated spike aggregation rather than direct binding.

2 citations

humanproteomics

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BiochemistryStructurePeer-reviewedMar 26, 2024

Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4

Meng Yuan, Linghang Peng, Deli Huang…·David A. Nemazee

This study reports the structures and mechanistic insights of PLD3 and PLD4, revealing their exonuclease activity, phosphatase function, and disease relevance.

13 citations

structural biologyexperimental assay

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