Author

Paris R. Watson

University of PennsylvaniaORCID 0000-0002-6990-525XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

David W. ChristiansoniD· 2 shared Benjamin A. Garcia· 1 shared Chao PengiD· 1 shared David EliezeriD· 1 shared E. James PeterssoniD· 1 shared Elizabeth R. RhoadesiD· 1 shared Grace Shin Hye ParkiD· 1 shared Hudson LeeiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

David W. ChristiansonORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJan 21, 2025

Investigation of Disease-Relevant Lysine Acetylation Sites in α-Synuclein Enabled by Non-canonical Amino Acid Mutagenesis

Marie Shimogawa, Minghao Li, Grace Shin Hye Park…·E. James Petersson

This study investigates how acetylation of specific lysine sites in α-synuclein affects aggregation and function, identifying K80 acetylation as a potential therapeutic target.

5 citations

humanproteomics

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BiochemistryJournal of Biological ChemistryPeer-reviewedSep 12, 2023

Crystal Structure of Histone Deacetylase 6 Complexed with (R)-Lipoic Acid, an Essential Cofactor in Central Carbon Metabolism

Paris R. Watson, Juana Goulart Stollmaier, David W. Christianson

This paper reports the crystal structure of HDAC6 complexed with (R)-dihydrolipoic acid and shows its redox-regulated interaction with the enzyme's active site.

12 citations

structural biologyexperimental assay

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