Author

Irina A. Okkelman

Ghent UniversityORCID 0000-0002-7014-6887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Ruslan I. DmitrieviD· 3 shared Sergey M. BorisoviD· 3 shared Angela C. DebruyneiD· 2 shared An HendrixiD· 1 shared Austin E.Y.T. LefebvreiD· 1 shared Bert DevriendtiD· 1 shared Cláudio PinheiroiD· 1 shared Dauwe BulckaeniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersPharmacology & Toxicology

Ruslan I. DmitrievORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 30, 2026

Electrically Enhanced Intraperitoneal Drug Delivery Resolved by Fluorescence Lifetime Imaging Microscopy

Nidda Saeed, Irina A. Okkelman, Sergey M. Borisov…·Wim P Ceelen

This study evaluates electrically enhanced intraperitoneal drug delivery using nanoparticles and fluorescence lifetime imaging microscopy to track drug penetration and intracellular release.

DOI 10.64898/2026.10.29.762719

humanrat

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Pharmacology & ToxicologyLight Science & ApplicationsPeer-reviewedAug 12, 2025

Fluorescence Lifetime Imaging Microscopy (FLIM) visualizes internalization and biological impact of nanoplastics in live intestinal organoids

Irina A. Okkelman, Hang Zhou, Sergey M. Borisov…·Ruslan I. Dmitriev

This paper uses FLIM to study nanoplastic interactions and effects in intestinal organoids, finding species-specific uptake and disruptions in mitochondrial function and inflammation.

28 citationstop 2%

mouseimaging

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Cancer BiologyACS NanoPeer-reviewedApr 30, 2024

Live microscopy of multicellular spheroids with the multi-modal near-infrared nanoparticles reveals differences in oxygenation gradients

Angela C. Debruyne, Irina A. Okkelman, Nina Heymans…·Ruslan I. Dmitriev

The paper introduces multi-modal near-infrared nanoparticles for live imaging of oxygenation gradients in 3D spheroids, revealing inverted oxygenation patterns and metabolic stratification.

59 citationstop 2%

humanimaging

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