Author
Karolinska University HospitalORCID 0000-0002-7015-3841Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Valeria Difilippo, Karim H. Saba, Karin Wallander…·Karolin H. Nord
SarcDBase is a tool that extracts and interprets genetic alterations from tumor sequencing data, showing high agreement with curated diagnoses in most cases.
Sólrún Kolbeinsdóttir, Vasilios Zachariadis, Muyi Yang…·Martin Enge
The paper analyzes subclonal gene dosage effects in cancer using DNTR-seq, finding additive and compensatory transcriptional impacts and identifying transient clonality in ovarian and soft tissue sarcomas.
Karim H. Saba, Valeria Difilippo, Emelie Styring…·Karolin H. Nord
This study identifies four subgroups of osteosarcomas based on genomic and transcriptomic analysis, revealing distinct mechanisms of CDK4 amplification in relation to MDM2 or TP53 alterations.