Hajime Murakami

This study identifies a conserved Red1 motif that interacts with Rec8 cohesin, promoting DSB formation and Mek1 activation during meiosis.

This study identifies Fun30 as essential for meiotic DNA break resection, showing it works with MRX and Exo1 to generate resection tracts necessary for recombination.

The paper shows that chromosome-autonomous feedback reduces meiotic DSBs when homologs engage, using yeast mutants with chromosomal abnormalities.

This study shows that Saccharomyces cerevisiae uses multiple mechanisms to control DSB formation on short chromosomes to prevent meiotic missegregation.

The paper identifies Mek1 as the kinase responsible for H3 T11 phosphorylation in meiosis and shows H3 T11ph serves as a marker of Mek1 activity.