Translational bioinformatics and machine learning framework for biomarker discovery, disease prediction, and patient profiling for precision medicine
Zeeshan Ahmed, Prithvi Govindareddy, William DeGroat…·Saman Zeeshan
Author
Rutgers, The State University of New JerseyORCID 0000-0002-7065-1699Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
9 papers
Recent·Most cited
Zeeshan Ahmed, Prithvi Govindareddy, William DeGroat…·Saman Zeeshan
Toshihiro Yamada, Kei Morikawa, Akira Fujiyama…·Yuichiro Arima
This study shows that hepatic ketogenesis reduces cardiac hypertrophy in HFpEF by maintaining beta-hydroxybutyrate levels, which modulate myocardial metabolism.
Rishabh Narayanan, Elizabeth Peker, William DeGroat…·Zeeshan Ahmed
This paper introduces 3D IntelliGenes, a tool for visualizing AI/ML results on multi-omics data to discover biomarkers and predict diseases through 3D clustering and feature analysis.
Rishabh Narayanan, William DeGroat, Elizabeth Peker…·Zeeshan Ahmed
VAREANT is a bioinformatics tool that simplifies variant data preprocessing, annotation, and AI/ML preparation for genomic analysis.
William DeGroat, Habiba Abdelhalim, Elizabeth Peker…·Zeeshan Ahmed
The paper develops a multimodal AI/ML framework to identify biomarkers and predict cardiovascular disease using multi-omics data, finding a 27-component signature with high predictive accuracy.
William DeGroat, Habiba Abdelhalim, Kush Patel…·Zeeshan Ahmed
This study identifies 18 significant transcriptomic biomarkers for cardiovascular disease with 96% accuracy using a combination of statistical tests and machine learning classifiers.
Zeeshan Ahmed, Saman Zeeshan, Nicholas Persaud…·Bruce T. Liang
The paper integrates gene expression, genetic variants, and clinical data from high-risk Heart Failure patients to identify differentially expressed genes and functionally relevant mutations associated with CVD.
Raghunandan Wable, Achuth Suresh Nair, Anirudh Pappu…·Zeeshan Ahmed
The paper develops a gene-disease-code database linking ICD codes with ACMG-approved genes to support genomic and clinical data integration for precision medicine.