Bettina Halwachs

The paper identifies PRMT5-CDK4 complex formation as a non-enzymatic regulator of cell cycle signaling, showing it modulates CDK4 interactions and mimics CDK4 inhibition.

The paper identifies switch mutations in ATGL that selectively disrupt interactions with specific regulatory proteins, linking these mutations to altered lipolysis activity and disease relevance.

This study identifies 51 direct interactions between SARS-CoV-2 proteins and human kinases, revealing altered kinase activity patterns and highlighting FER kinase inhibition by ORF6.