Author

Giuseppe Marotta

Azienda Ospedaliera Universitaria SeneseORCID 0000-0002-7209-1613Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Carmela TangrediiD· 2 shared Cosima T. BaldariiD· 2 shared Francesca FinettiiD· 2 shared Laura PatrussiiD· 2 shared Livio TrentiniD· 2 shared Ludovica LoprestiiD· 2 shared Nagaja CapitaniiD· 2 shared Vanessa TatangeloiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Carmela TangrediORCID

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2 papers

Recent·Most cited

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedFeb 4, 2025

Thrombospondins 1 and 4 undergo coordinated transport to multicore cytotoxic granules to regulate SMAP biogenesis and function in CTL-mediatedcytotoxicity

Chiara Cassioli, Nagaja Capitani, Claire C. Staton…·Cosima T. Baldari

This study shows TSP-4 is required for TSP-1 association with lytic granules and SMAP-mediated cytotoxicity in CTLs, and its expression is suppressed in CLL cell supernatants.

11 citations

humanproteomics

𝕏 PostBluesky

Cancer BiologyCell Death and DiseasePeer-reviewedFeb 15, 2024

Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia

Gioia Boncompagni, Vanessa Tatangelo, Ludovica Lopresti…·Cosima T. Baldari

This study shows that IL-9 secreted by leukemic cells suppresses CTL-mediated killing in CLL by increasing PD-1 expression and impairing immune synapse formation.

9 citations

mousehuman

𝕏 PostBluesky