Gail McConnell

This paper introduces a background correction method for Fourier ptychographic microscopy images that preserves specimen information and improves quantitative analysis.

This paper applies Fourier ptychographic microscopy to label-free imaging of large botanical specimens, achieving high-resolution imaging over a large field of view.

The paper uses multimodal imaging to show that polymicrobial biofilms degrade silicone voice prosthesis implants by invading the device and releasing silicone particles.

OpenFPM provides an open-source, low-cost Fourier ptychographic microscopy platform for high-resolution biomedical imaging.

CASC reduces microscopy image file sizes by removing spatial redundancy while preserving object-level biological structures.

ABC3D quantifies 3D biofilm morphology using fractal, textural, and statistical features, showing nutrient availability and cell shape influence biofilm structure in E. coli.

This paper presents a low-cost, rapid method to fabricate solid immersion lenses (SILs) that enhance optical microscope resolution, achieving performance comparable to commercial glass SILs at a fraction of the cost.

This paper develops low-cost 3D printed lenslet arrays for super-resolution microscopy, achieving resolution comparable to commercial optics.

This study uses STED microscopy to improve resolution of Candida albicans ultrastructure, showing better performance than confocal microscopy for tracking sub-cellular components over time.

The paper introduces a 3D-printed lens-biprism element that improves image contrast in stereomicroscopy by enhancing illumination uniformity.

This paper introduces SQUASSH, a convolutional neural network that fits structural models to fluorescence microscopy data to quantify variability across biological scales.

This study develops a silicone elastomer colonization model to investigate C. albicans and S. aureus biofilm formation on medical devices, revealing morphological differences based on C. albicans cell morphotypes.

This study examines collagen levels in tonsils of patients with acute recurrent tonsillitis and obstructive sleep apnoea to better understand disease pathophysiology.

PerfectlyAverage determines optimal averaging parameters in laser scanning fluorescence microscopy by analyzing SNR, photobleaching, and PSD to reduce acquisition time.

This study quantifies oxygen gradients in E. coli biofilm transport channels using three sensing methods, revealing anoxic conditions that challenge previous assumptions about channel openness.

The paper describes a low-cost 3D-printed optical microscope capable of sub-cellular resolution for histological imaging, using affordable components and open design for replication.

This paper demonstrates a method to achieve high-resolution imaging over a large field of view using SRRF and Mesolens, achieving 446.3 nm resolution with minimal error.

This study quantifies how E. coli biofilm channel complexity changes with cell shape and growth conditions using fractal analysis.

The paper introduces a 3D optical mesoscopy method to quantify GLUT4 levels in intact mouse hearts and shows gender-dependent expression changes with high fat diet.

The paper presents low-cost 3D printed lenses for brightfield and fluorescence microscopy, demonstrating sub-cellular resolution comparable to commercial optics.

This study develops a low-cost method to produce high-quality 3D printed lenses comparable to commercial glass lenses for optical imaging applications.

FISHtoFigure is a software tool for analysing smFISH data, enabling automated spatial analysis of mRNA expression without requiring bioinformatics expertise.

This paper introduces a neural network method to restore fluorescence microscopy images by reducing background signals from non-specific labeling.

The paper demonstrates the use of the Mesolens to image sub-cellular details in intact Drosophila larvae and adults without dissection.

This paper introduces a 340/380 nm LED illuminator for Fura-2 ratiometric Ca2+ imaging, achieving better than 5 nM precision and faster acquisition speeds for detecting Ca2+ events in live cells.