Guo‐Qiang Chen

This study introduces RelaVDEP, a virtual directed evolution pipeline using reinforcement learning to accelerate protein mutation discovery, showing improved catalytic activity in PETase through novel mutations.

This study shows that 3-hydroxybutyrate reduces liver fibrosis in mice by improving mitochondrial function and reducing oxidative stress.

This paper introduces PhASE, a system for dynamically controlling enzymatic reactions in E. coli using light-responsive compartments formed by liquid-liquid phase separation, showing enhanced reaction efficiency.