Yap Seng Chong

This study shows that the development of long-range cortical connections leads to the emergence of hierarchical functional modes in the human cortex, shifting from geometrically driven patterns to sensory-association organization.

This study examines the impact of prenatal PFAS exposure on childhood brain development using MRI data, finding associations with cortical surface area and white matter microstructure changes.

This paper develops and benchmarks BrainAge models using multi-modal neuroimaging data from childhood cohorts to distinguish healthy from symptomatic developmental trajectories.

This study identifies two ASD subgroups with distinct brain morphology using cross-cultural datasets, highlighting key brain regions associated with subgroup characteristics and autistic traits.

This study tests a brain age model on Singaporean children and elderly, finding that brain age gap change relates to future executive function in both groups.

This paper introduces DELSSOME, a deep learning framework that accelerates biophysical brain circuit model optimization, enabling faster parameter estimation and lifespan trajectory analysis of cortical E/I ratios.

The paper shows diet intervention alters sncRNA expression in human sperm, linking paternal nutrition to offspring health through epigenetic changes.

The paper investigates how life stages affect the human skin microbiome and lipid mediators, finding microbial correlations with lipid profiles and cytokine production.

The paper introduces a longitudinal dataset of school-age children and adolescents in China, detailing its design, sampling, and neuroimaging measurements.

The paper estimates the whole-cortex excitation-inhibition ratio using fMRI and shows it declines during youth, with lower ratios linked to better cognitive performance in children.

The paper develops homotopic local-global parcellations of the human cerebral cortex using resting-state and task-fMRI, showing improved homogeneity and lateralization compared to existing parcellations.

The paper defines a homeostatic inflammation signature in the placenta, creates a polygenic score, and shows its protective effects on cardiovascular and depressive outcomes using UK Biobank data.

RAPTOR provides a secure, cloud-native genomics repository with a five-safes framework to ensure compliance and data protection for genomic research.

The paper introduces brain charts as a standardized resource for benchmarking brain morphology across the human lifespan using MRI data from a large and diverse cohort.

The paper maps the developmental and intergenerational changes in the human circulatory lipidome and identifies lipid signatures associated with obesity risk in mothers and offspring.