Systems BiologyNucleic Acids ResearchPeer-reviewed
The molecular aetiology of tRNA synthetase depletion: induction of a GCN4 amino acid starvation response despite homeostatic maintenance of charged tRNA levels
Matthew R. McFarland, Corina D Keller, Brandon M. Childers…·Ian Stansfield
The paper investigates how depletion of the glutamine tRNA synthetase (Gln4p) in yeast triggers a GCN4 amino acid starvation response despite maintaining charged tRNA levels.
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