Stephen L. Mathias

The paper develops a deep learning framework to predict kinase-ligand interactions using molecular structure and Gene Ontology data from the Pharos database.

TIGA aggregates and ranks gene-trait associations from GWAS data to prioritize drug targets using statistical and bibliometric evidence.

The paper introduces the Drug Target Ontology (DTO) to classify and integrate drug discovery data by formalizing druggable protein targets and their characteristics.