BioengineeringbioRxivPreprint
De novo functional discovery of peptide-MHC restricted CARs from recombinase-constructed large-diversity monoclonal T cell libraries
Zening Wang, Abhijit Sarkar, Xin Ge
The paper develops a method to discover functional TCR-mimic CARs by combining library construction and screening, identifying effective CARs against specific tumor antigens.
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