GeneticsCell ReportsPeer-reviewed
Human macroH2A1 drives nucleosome dephasing and genome instability in histone-humanized yeast
Max A. B. Haase, Luciana Lazar‐Stefanita, Guðjón Ólafsson…·Jef D. Boeke
This study replaces human variant histones in yeast, showing macroH2A1 disrupts chromatin organization and causes genome instability.