Michał Komorowski

The paper quantifies the discrepancy between population-average and single-cell suppression of pY-STAT1/3 by JAK inhibitors, showing that strong average suppression leaves many cells with elevated responses.

This paper introduces fractional response analysis to quantify single-cell signaling responses and finds cytokine responses scale logarithmically with dose.

This study quantifies information transfer fidelity in gene expression models, showing transcriptional control has higher capacity than translational control, and feedback reduces overall capacity.