Sophia R. Meyer

This paper uses patient-derived liver organoids and machine learning to identify hepatotoxic compounds by analyzing morphological changes, achieving high accuracy in distinguishing toxicants from non-toxicants.

This paper develops a long-term in vitro model of human colonic epithelium that maintains barrier function for up to 30 days and responds to various challenges.

This paper introduces a high-throughput microfluidic liver chip system using human liver organoids to model drug-induced liver injury with improved sensitivity and prolonged drug exposure capabilities.