Author

Edmond W. Box

University of MiamiORCID 0000-0002-7316-8539Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:statistical model· 1

Frequent Co-Authors

Austin R. DoschiD· 2 shared Haleh AmirianiD· 2 shared Jashodeep DattaiD· 2 shared Manan S. PateliD· 2 shared Nagaraj S. NagathihalliiD· 2 shared Nipun B. MerchantiD· 2 shared Siddharth MehraiD· 2 shared Sudhakar JinkaiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Austin R. DoschORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 8, 2025

Targeting CREB remodels the immune microenvironment to enhance immunotherapy responses in pancreatic cancer

Siddharth Mehra, Supriya Srinivasan, Sudhakar Jinka…·Nagaraj S. Nagathihalli

This study shows that targeting CREB reduces immunosuppression in pancreatic cancer by altering macrophage polarization and enhancing immunotherapy effectiveness.

DOI 10.64898/2025.12.04.691935

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2025

CREB drives acinar cells to ductal reprogramming and promotes pancreatic cancer progression in preclinical models of alcoholic pancreatitis

Supriya Srinivasan, Siddharth Mehra, Sudhakar Jinka…·Nagaraj S. Nagathihalli

This study shows CREB promotes acinar-to-ductal reprogramming and pancreatic cancer progression in alcoholic pancreatitis models by enhancing fibrosis and tumor growth.

9 citations

mousebulk RNA-seq

𝕏 PostBluesky