Alexander T. Honkala

PEACH is a PyTorch-based archetype analysis tool for scRNA-seq data that identifies pure extremal cell states and their tradeoffs using a constrained autoencoder.

This study tracks microbiome changes across four body sites in 86 participants over six years, revealing site-specific stability, individualized dynamics, and altered patterns in insulin-resistant individuals.

The paper uses long-read sequencing to identify novel SARS-CoV-2 transcripts and variants, revealing a complex transcriptome landscape.