Steven K. Backues

The paper investigates the distinct roles of Atg3 and Atg10 in autophagosome formation in yeast, showing Atg3 affects lipidation and size while Atg10 controls number.

Auto-AVS simulates autophagic vacuoles in yeast to test stereological assumptions, finding no effect of body deformation on section statistics but discrepancies in body-number estimates.

The paper screens Atg11 residues in yeast to identify binding sites for Atg9 during selective autophagy but fails to find specific essential residues.

This paper introduces a validated Cellpose 2.0 model for automated segmentation of autophagic bodies in yeast TEM images, achieving accuracy comparable to human experts and significantly reducing manual effort.