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The paper combines AlphaFold 3 with microscale thermophoresis to study aptamer-protein interactions, finding that structural predictions are not reliable predictors of binding strength.

This study uses a porcine model to investigate anaphylactoid reactions caused by a carbon-cellulose cartridge, revealing mechanisms of cardiovascular collapse and shock.

This study selects DNA aptamers targeting Streptococcus mutans GbpC to inhibit biofilm formation, showing 30% reduction in wild-type strains and no effect on GbpC-deficient strains.

This study identifies LIFERING as an E3 ligase that ubiquitinates IBR3, linking DNA damage response to auxin regulation in plant roots.

This study investigates how mRNA-LNP vaccines trigger complement activation and cytokine production, linking these processes to inflammatory adverse events and suggesting potential therapeutic strategies.

This study identifies aptamers that inhibit RSV infection by targeting the prefusion F protein, with modified nucleotides improving their stability and efficacy.