Jasper P. Hof

This paper introduces GenSep, a framework to quantify genetic separability of disease subtypes, showing current PRSs fall short of theoretical limits.

StratGWAS improves GWAS power by incorporating phenotype heterogeneity while maintaining specificity, identifying more significant loci in depression and other traits.

LDAK-KVIK is a mixed-model association analysis tool that outperforms existing methods in power and efficiency for quantitative and binary phenotypes.