Author
University of Electronic Science and Technology of ChinaORCID 0000-0002-7475-7888Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Tingting Fan, Yanhao Cheng, Yuechao Wu…·Yong Zhang
This study develops and evaluates TadA-8e-derived cytosine and dual base editors in plants, showing high efficiency, purity, and specificity with no off-target effects.
Yuechao Wu, Qiurong Ren, Zhaohui Zhong…·Yong Zhang
The paper analyzes off-target effects of PAM-relaxed Cas9 editors in rice using whole-genome sequencing and finds ABE8e causes ~500 A-to-G mutations per plant at TA motifs.
Xu Dong Tang, Guanqing Liu, Jianping Zhou…·Yong Zhang
This study uses whole-genome sequencing to analyze off-target mutations in Cas9 and Cpf1-edited rice, finding most mutations arise from tissue culture rather than nuclease activity.