Molecular BiologybioRxivPreprint
miR-6818-5p Drives Ovarian Granulosa Cell Dysfunction in PCOS via Targeting HSD17B2 and Modulating PI3K/Caspase-9 Axis
DOI 10.64898/2026.05.22.726113
Author
Tao Zhang
Yangzhou UniversityORCID 0000-0002-7897-0205Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2018-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 41 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
- Molecular BiologyNature CommunicationsPeer-reviewed
High performance TadA-8e derived cytosine and dual base editors with undetectable off-target effects in plants
Tingting Fan, Yanhao Cheng, Yuechao Wu…·Yong Zhang
This study develops and evaluates TadA-8e-derived cytosine and dual base editors in plants, showing high efficiency, purity, and specificity with no off-target effects.
56 citationstop 1% - GenomicsThe Plant GenomePeer-reviewed
Genome-wide investigation of multiplexed CRISPR-Cas12a-mediated editing in rice
Yingxiao Zhang, Yuechao Wu, Gen Li…·Yiping Qi
The paper investigates off-target effects of multiplexed CRISPR-Cas12a editing in rice using whole-genome sequencing and finds low-frequency chromosomal deletions and duplications with high DSB numbers.
- GeneticsPlant Biotechnology JournalPeer-reviewed
Genome-wide analyses of PAM-relaxed Cas9 genome editors reveal substantial off-target effects by ABE8e in rice
Yuechao Wu, Qiurong Ren, Zhaohui Zhong…·Yong Zhang
The paper analyzes off-target effects of PAM-relaxed Cas9 editors in rice using whole-genome sequencing and finds ABE8e causes ~500 A-to-G mutations per plant at TA motifs.
56 citationstop 5% - GeneticsChromosome ResearchPeer-reviewed
A universal chromosome identification system for maize and wild Zea species
Guilherme Tomaz Braz, Lívia do Vale Martins, Tao Zhang…·Jiming Jiang
The paper develops a universal chromosome identification system for maize and wild Zea species using FISH probes, enabling accurate identification and revealing chromosomal differences between species.
- Molecular BiologyGenome biologyPeer-reviewed
A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 nucleases in rice
Xu Dong Tang, Guanqing Liu, Jianping Zhou…·Yong Zhang
This study uses whole-genome sequencing to analyze off-target mutations in Cas9 and Cpf1-edited rice, finding most mutations arise from tissue culture rather than nuclease activity.
306 citationstop 1%