Author
University of Massachusetts Chan Medical SchoolORCID 0000-0002-7523-2602Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Feng He, Chan Wu, Allan Jacobson
The paper identifies cis-binding elements in Dcp2 that form distinct decapping complexes, controlling mRNA targeting specificity in yeast.
Robin Ganesan, Kotchaphorn Mangkalaphiban, Richard E. Baker…·Allan Jacobson
The paper investigates the timing and nature of Upf1, Upf2, and Upf3 ribosome association during NMD, revealing progressive polysome association and an early Upf1:80S complex.
Kotchaphorn Mangkalaphiban, Feng He, Robin Ganesan…·Allan Jacobson
The paper investigates stop codon readthrough in yeast using ribosome profiling and bioinformatics to identify mRNA features influencing termination efficiency.
Chan Wu, Bijoyita Roy, Feng He, Allan Jacobson
The paper investigates how the position of nonsense codons affects readthrough efficiency in yeast, showing that poly(A)-binding protein regulates translation termination.
Feng He, Alper Celik, Chan Wu, Allan Jacobson
The paper identifies that decapping activators target specific subsets of inefficiently translated mRNAs and reveal the role of the Dcp2 C-terminal domain in both positive and negative regulation.