Author

Lin Bai

Peking UniversityORCID 0000-0002-7535-7819Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:fungi (other)· 1

Frequent Co-Authors

Abzer Kelminal Pakkir Mohamed ShahiD· 1 shared Alejandro Pérez‐GarcíaiD· 1 shared Alicia Isabel Pérez‐LorenteiD· 1 shared Antoine LoquetiD· 1 shared Antonio de VicenteiD· 1 shared Axelle GrélardiD· 1 shared Daniel PetrasiD· 1 shared David Vela‐CorcíaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Abzer Kelminal Pakkir Mohamed ShahORCID

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2 papers

Recent·Most cited

BioengineeringNature Structural & Molecular BiologyPeer-reviewedSep 16, 2026

Structure-guided discovery and engineering of miniature CRISPR-Cas12m for epigenome editing

Tao Yu, Meng Ji, Donglin Yu…·Kailong Li

This paper identifies and engineers a miniature CRISPR-Cas12m variant for epigenome editing, demonstrating its effectiveness in human cells and a mouse model of HBV infection.

DOI 10.1038/s41594-026-01890-9

humanmouse

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MicrobiologyCommunications BiologyPeer-reviewedOct 3, 2024

Cyclo(Pro-Tyr) elicits conserved cellular damage in fungi by targeting the ATPase Pma1 in plasma membrane domains

David Vela‐Corcía, Jesús Hierrezuelo, Alicia Isabel Pérez‐Lorente…·Diego Romero

This study identifies cyclo(Pro-Tyr) as a metabolite that disrupts eukaryotic cellular membranes by targeting Pma1 ATPase in microdomains, inducing oxidative stress and membrane fluidity changes in fungi and nematodes.

15 citationstop 5%

fungi (other)C. elegans

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