GeneticsbioRxivPreprint
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier
Casey A. Gifford, Sanjeev S. Ranade, Ryan Samarakoon…·Deepak Srivastava
The paper shows that a congenital heart defect can result from three inherited heterozygous missense variants in MYH7, MKL2, and NKX2-5.