Author

P Mahavadi

Justus-Liebig-Universität GießenORCID 0000-0002-7580-4738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A Guenther· 1 shared Ana Lúcia CoelhoiD· 1 shared Andreas GüntheriD· 1 shared BreAnne MacKenzieiD· 1 shared Brecht CreynsiD· 1 shared Brian Windsor· 1 shared C Ruppert· 1 shared Clemens AigneriD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A Guenther

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2 papers

Recent·Most cited

Pharmacology & ToxicologyiSciencePeer-reviewedAug 26, 2025

Pre-clinical proof-of-concept of anti-fibrotic activity of caveolin-1 scaffolding domain peptide LTI-03 in ex vivo precision cut lung slices from patients with Idiopathic Pulmonary Fibrosis

BreAnne MacKenzie, Poornima Mahavadi, Yago Amigo Pinho Jannini de Sá…·Andreas Günther

This study evaluates the anti-fibrotic effects of LTI-03 in IPF patient-derived precision cut lung slices, showing dose-dependent reduction of fibrotic markers.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintMar 23, 2019

Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition

RM Wasnick, M Korfei, K Piskulak…·A Guenther

Notch1 inhibition restores alveolar epithelial differentiation, reduces surface tension, and reverses matrix deposition in lung fibrosis.

DOI 10.1101/580498

humanbulk RNA-seq

𝕏 PostBluesky