Yennifer Delgado

This study integrates multi-omics data to compare endothelial cell responses to New and Old World hantaviruses, identifying species-specific immune and cellular mechanisms.

This study shows the SARS-CoV-2 nucleocapsid protein drives hyperinflammation and vascular leakage in macrophages via Toll-like receptor signaling, contributing to severe COVID-19 complications.

This study shows HIV-1 infected immune cells alter cervical cancer pathways through paracrine signals, with upregulated PI3K-AKT and interferon-stimulated genes.

This study identifies phosphoregulation of nuclear protein complexes by HIV-1 latency-reversing agents, revealing shared mechanisms across different LRAs.

The paper shows HIV Vpr degrades CCDC137 via a nucleolar ATR pathway, causing nucleolar stress and ribosome biogenesis repression, independent of G2/M arrest.

The paper identifies human kinase motifs in viral proteomes, showing enrichment for stress and immune-related kinases and their phosphorylation in infected cells.

The paper identifies potent host-targeted antivirals against Mpox virus through high-throughput screening of a kinase inhibitor library, showing efficacy in vitro and in a mouse model.

This study identifies CebN, a Chlamydia trachomatis effector that targets nucleoporins and Rae1 to disrupt STAT1 nuclear import, aiding bacterial survival.