Marco Tonelli

This study identifies two distinct conformational equilibria in arrestin-2 that underlie its pre-activation state in solution.

This study identifies urea carbon salvage as a mechanism enabling hibernating squirrels to reuse urea and mucins for energy during fasting.

This study investigates the structure, folding kinetics, and dynamics of long poly(UG) RNAs, revealing a dynamic model for segmental register exchange and double pUG fold formation.

The paper reports NMR resonance assignments for EmrE, a multidrug transporter, using solution and solid-state NMR techniques at specific pH conditions.

This paper introduces a method to control pH in NMR samples using light-activated photoacids, enabling non-invasive and precise pH modulation for studying protonation states in proteins.

This paper investigates the binding specificity of CECR2-BRD to acetylated histone and non-histone ligands, revealing distinct binding modes and functional roles in chromatin regulation and inflammation.

This study uses biophysical and computational methods to characterize the structure of human Cdt1, revealing 'folded over' conformations that suggest a scaffold function.

The paper identifies a novel RNA quadruplex structure, the pUG fold, that drives gene silencing in C. elegans and is present in human non-coding RNAs.