Che-Yi Lin

This study presents a chromosome-anchored genome assembly of Asymmetron lucayanum, revealing genome architecture and gene evolution in cephalochordates.

This study creates a 3D amphioxus brain atlas using single-nucleus RNA-seq and spatial transcriptomics, revealing ancestral brain organization and highlighting vertebrate innovations.

The paper identifies an ancient regulatory syntax, SFZE, associated with brachyury across non-chordate and chordate species, suggesting its role in notochord origin through co-option of conserved elements.

This paper analyzes the evolutionary dynamics of FoxQ2 transcription factors across metazoans, identifying three ancient paralogs and revealing conserved and novel expression patterns in chordates.

This study presents chromosome-level genome assemblies of two hemichordates to infer deuterostome ancestral chromosomal architecture and lineage-specific modifications.