MicrobiologyJournal of VirologyPeer-reviewed
V3 tip determinants of susceptibility to inhibition by CD4-mimetic compounds in natural clade A human immunodeficiency virus (HIV-1) envelope glycoproteins
Saumya Anang, Shijian Zhang, Christopher J. Fritschi…·Joseph Sodroski
This study identifies residue changes in the gp120 V3 loop that influence susceptibility of HIV-1 Envs to CD4-mimetic compounds, showing how variations outside the binding site affect inhibitor sensitivity.
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