Author

Jan Fiala

Utrecht UniversityORCID 0000-0002-7753-8170Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Albert J. R. HeckiD· 3 shared Athanasios SmyrnakisiD· 1 shared Constantinos PatiniosiD· 1 shared Danique M.H. van RijswijckiD· 1 shared Detlev SuckauiD· 1 shared Dimitris K PapanastasiouiD· 1 shared Dina SchusteriD· 1 shared Elena E. PohliD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiochemistry

Albert J. R. HeckORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 29, 2025

A prototype timsOmni platform enables confident annotation of key hypervariable regions of IgG immunoglobulins using low- and high-energy electron-based fragmentation.

Simon Ollivier, Dina Schuster, Danique M.H. van Rijswijck…·Albert J. R. Heck

1 citation

proteomicsexperimental assay

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Molecular BiologybioRxivPreprintMar 19, 2025

Structure of an oxygen-induced tubular nanocompartment in Pyrococcus furiosus

Wenfei Song, Jan Fiala, Ioannis Skalidis…·Friedrich G. Förster

The paper identifies oxygen-induced tubular nanocompartments in Pyrococcus furiosus using proteomics and cryo-EM, revealing their structure and role in ROS protection.

DOI 10.1101/2025.03.19.643997

proteomicselectronic health records

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BiochemistryACS Chemical BiologyPeer-reviewedJul 25, 2024

Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs

Wouter van Bergen, Kristina Žuna, Jan Fiala…·Marc P. Baggelaar

This study compares two EGFR-targeted drugs using ABPP to reveal site-specific binding differences and off-target effects at low concentrations.

5 citations

humanproteomics

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