Author

Christel Claes

Leuven Stem Cell InstituteORCID 0000-0002-7765-0445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Adrian ListoniD· 1 shared Alessandra QuartaiD· 1 shared Amaia M. ArranziD· 1 shared Annerieke S. R. SierksmaiD· 1 shared Anton De SpiegeleeriD· 1 shared Bart De StrooperiD· 1 shared Bart M. J. De SpiegeleeriD· 1 shared Carlo Sala FrigerioiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Adrian ListonORCID

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2 papers

Recent·Most cited

NeuroscienceScientific ReportsPeer-reviewedMay 21, 2021

PapRIV, a BV-2 microglial cell activating quorum sensing peptide

Yorick Janssens, Nathan Debunne, Anton De Spiegeleer…·Bart M. J. De Spiegeleer

This study investigates the ability of the quorum sensing peptide PapRIV to activate BV-2 microglia and cross biological barriers, showing in vitro activation and in vivo presence.

32 citations

mouseexperimental assay

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NeuroscienceNature NeurosciencePeer-reviewedOct 28, 2019

Stem cell derived human microglia transplanted in mouse brain to study genetic risk of Alzheimer's Disease

Renzo Mancuso, Johanna Van Den Daele, Nicola Fattorelli…·Bart De Strooper

The paper demonstrates that human microglia derived from embryonic stem cells can engraft mouse brains and express Alzheimer's risk genes when exposed to Aβ, offering a new model to study genetic risk in AD.

295 citationstop 1%

mousehuman

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