Author

Lionel Berthoux

Université du Québec à Trois-RivièresORCID 0000-0002-7776-5058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Ghada Elfayres· 2 shared Benoı̂t BarbeauiD· 1 shared Chen LiangiD· 1 shared Isabel Desgagné‐PenixiD· 1 shared Natacha MérindoliD· 1 shared Qinghua PaniD· 1 shared Ronja FriedhoffiD· 1 shared Yong XiaoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Ghada Elfayres

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MicrobiologyMicrobiology ResearchPeer-reviewedJun 11, 2025

A novel SARS-CoV-2-derived infectious vector system

Ghada Elfayres, Yong Xiao, Qinghua Pan…·Lionel Berthoux

The paper develops a SARS-CoV-2-derived viral vector system for antiviral drug screening and research, showing it can infect human cells and is sensitive to remdesivir and interferons.

DOI 10.3390/microbiolres16060125

humanspatial transcriptomics

𝕏 PostBluesky

MicrobiologyPLoS ONEPeer-reviewedAug 16, 2024

T7 RNA polymerase-independent expression of reporter genes from a T7 promoter-driven SARS-CoV-2 replicon-encoding DNA in human cells

Ronja Friedhoff, Ghada Elfayres, Natacha Mérindol…·Lionel Berthoux

This study shows that a SARS-CoV-2 replicon DNA can express reporter genes in human cells without requiring T7 RNA polymerase or RNA replication.

1 citation

humanDNA methylation

𝕏 PostBluesky