GeneticsThe CRISPR JournalPeer-reviewed
The FusX TALE Base Editor (FusXTBE) for rapid mitochondrial DNA programming of human cells in vitro and zebrafish disease models in vivo
Ankit Sabharwal, Bibekananda Kar, Santiago Restrepo-Castillo…·Stephen Carl Ekker
The paper introduces FusXTBE, a TALE base editor for editing mtDNA in human cells and zebrafish, achieving high editing efficiency and precision.