Author

Meyling Hua-Chen Cheok

Centre National de la Recherche ScientifiqueORCID 0000-0002-7820-8026Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Claude PreudhommeiD· 2 shared Djohana Laurent· 2 shared Nicolas PottieriD· 2 shared Abrar AlharbiiD· 1 shared Adam Ivey· 1 shared Adeline BarthélémyiD· 1 shared Adriana PleșaiD· 1 shared Alan K. BurnettiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Claude PreudhommeORCID

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4 papers

Recent·Most cited

Genetic & Genomic MedicineGenes & DiseasesPeer-reviewedSep 1, 2026

Assessing the clinical significance of a novel rare variant in Loeys-Dietz Syndrome by combining AI-driven modelling and cell biology

Nihad Boukrout, Clément Delage, Thomas Comptdaer…·Nicolas Pottier

The paper evaluates a novel TGFBR2 variant using AI and cell biology to determine its pathogenicity in Loeys-Dietz Syndrome.

DOI 10.1016/j.gendis.2026.102443

humanproteomics

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BioinformaticsbioRxivPreprintJan 7, 2026

Graph-based Drug Decomposition for Anticancer Response Modeling

Stefano Nasini, Luis Fernando Pérez Armas, Oussama Bouaggad…·Meyling Hua-Chen Cheok

This paper models ex vivo drug response in pediatric AML by decomposing drug molecules into structured features and using graph-based methods to identify key molecular predictors of cellular viability.

DOI 10.64898/2026.01.06.697864

humanstatistical model

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Cancer BiologybioRxivPreprintSep 20, 2023

Tetraspanin CD81 promotes leukemia stem cell function and represents a new therapeutic vulnerability in acute myeloid leukemia

Fanny Gonzales, Pauline Peyrouze, Thomas Boyer…·Meyling Hua-Chen Cheok

This study identifies CD81 as a marker of aggressive AML and shows anti-CD81 therapy improves survival in AML models.

DOI 10.1101/2023.09.20.558656

mousebulk RNA-seq

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Genetic & Genomic MedicineNature CommunicationsPeer-reviewedOct 29, 2021

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Wei‐Yu Lin, Sarah Elizabeth Fordham, Eric A. Hungate…·James M. Allan

This study identifies two genome-wide significant susceptibility loci for acute myeloid leukemia through a meta-analysis of GWAS data.

44 citations

humanGWAS summary statistics

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