Yuan Xue

The paper identifies SPIC-dependent VCAM1+ macrophages as drivers of granuloma formation and bacterial persistence during Salmonella infection.

This study shows that injury in the acoel Convolutriloba longifissura triggers coordinated responses between the host and its symbiotic algae, mediated by the runt transcription factor.

The paper introduces the self-assembling manifold algorithm to improve gene relevance quantification and dimensionality reduction in single-cell RNA sequencing data, showing it outperforms existing methods in identifying stem cell populations and across multiple datasets.