GenomicsCell GenomicsPeer-reviewed
High-throughput screening of human genetic variants by pooled prime editing
Michael Herger, Christina M. Kajba, Megan Buckley…·Gregory M. Findlay
This paper introduces a pooled prime editing platform in haploid human cells to assess the functional effects of genetic variants, showing high accuracy in identifying loss-of-function variants and pathogenic non-coding variants.
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