Shawna Marie Hubert

The paper introduces ICeITH, a Bayesian model to assess intratumor heterogeneity of tumor-infiltrating leukocytes using multi-region gene expression data, showing improved accuracy over existing methods.

The paper investigates how anti-cancer immunity evolves from preneoplasia to invasive lung adenocarcinomas, identifying changes in immune response and molecular features that may facilitate immune evasion.

The paper identifies and characterizes GSTA3 mRNA and protein sequences in dog, goat, and opossum, showing high conservation with human and horse GSTA3 and suggesting differences in enzymatic activity.

The paper quantifies tumor-specific total mRNA expression from bulk data and shows its association with clinical outcomes across 15 cancer types.

This study examines genomic and TCR repertoire heterogeneity in SCLC, finding that lower TCR heterogeneity and mutational burden correlate with better survival.

This study identifies a polygenic, heritable basis for wooden breast in broilers through transcriptomic analysis and pathway enrichment, revealing complex molecular mechanisms beyond myopathy.