Author

Subrahmanya Vallabhapurapu

Children's Hospital of PittsburghORCID 0000-0002-7924-0175Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Aaron Y. MochizukiiD· 1 shared Alberto DelaidelliiD· 1 shared Andrew M. BaschnageliD· 1 shared Andrew M. DonsoniD· 1 shared Aniruddha Sunil KarveiD· 1 shared Antonio C.T. Cobos· 1 shared Baoli HuiD· 1 shared Bhagyalakshmi Manikandan· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Aaron Y. MochizukiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 7, 2026

Adenosylhomocysteinase drives epigenetic and metabolic reprogramming in ZFTA-RELA ependymoma

Navneesh Yadav, Olivia Pelcher, Raja Gopal Reddy Mooli…·Kulandaimanuvel Antony Michealraj

This study identifies AHCY as a key driver of epigenetic and metabolic reprogramming in ZFTA-RELA ependymomas, revealing its role in promoting tumor growth through pyrimidine synthesis and asparagine dependency.

DOI 10.64898/2026.10.06.757085

humanbulk RNA-seq

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Cancer BiologyCancersPeer-reviewedSep 15, 2024

GABA(A) receptor activation drives GABARAP-Nix mediated autophagy to radiation-sensitize primary and brain-metastatic lung adenocarcinoma tumors

Debanjan Bhattacharya, Riccardo Barrile, Donatien Kamdem Toukam…·Soma Sengupta

This paper shows that activating GABA(A) receptors in lung cancer cells triggers autophagy via GABARAP-Nix interaction, enhancing radiation sensitivity and reducing toxicity in preclinical models.

15 citations

mouseexperimental assay

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