Arthur E. H. Bentlage

This paper develops an enzymatic platform to synthesize diverse mAb glycoforms and uses them to study α-Gal immunogenicity and FcγR binding.

This study characterizes FCRL5 as a low-affinity IgG-Fc receptor with distinct binding properties, showing preference for afucosylated IgG and identifying key residues for interaction.

This study shows that IgG hexamerization is critical for triggering acute lung injury and suggests therapeutic strategies targeting hexamer formation.