Yuanyuan Chen

scRGP predicts single-cell genetic perturbation transcriptional responses using rank-based deep learning, improving performance over existing methods for single, double, and cross-cell-line perturbations.

This study identifies the antifungal mechanism of quinofumelin by showing it targets FgDHODHII in the pyrimidine biosynthesis pathway, inhibiting mycelial growth in Fusarium species.

This study uses a Transformer model to design novel succinate dehydrogenase inhibitors against agricultural fungi, resulting in potent antifungal compounds through virtual screening and optimization.

The paper fills a gap in 3D spatial transcriptomics by providing data from E9.5 and E11.5 mouse embryos, enabling detailed analysis of organogenesis with a new open-access database.

NcPath integrates and visualizes miRNA and lncRNA interactions with KEGG pathways, enabling enrichment analysis of non-coding RNA involvement in biological processes.

Deep6mA is a deep learning framework for identifying DNA 6mA sites, achieving high accuracy across species and revealing conserved sequence patterns and regulatory roles of 6mA.